10/24/12 - Dr. Hildy™ Welcomes Dr. Dinender Singla - Stem Cells 101

~~Dr. Dinender Singla~~

Dr. Hildy™ Welcomes Dr. Dinender Singla, Author

Stem Cell Biology: Basic Concepts to Frontiers,
Students Edition

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OneCellOneLight™Radio | Blog Talk Radio
Wednesday, October 24, 2012 1:00-3:00PM Pacific
(2-4pm Mountain; 3-5pm Central, 4-6pm Eastern)

CLICK Here to Listen Live and for the archives after the show date: http://www.blogtalkradio.com/onecellonelightradio/2012/10/24/102412-dr-hildy-and-dr-dinender-singla–stem-cells-101

(**CLICK ON IMAGES TO ENLARGE**)

This week on One Cell One Light Radio, Dr. Hildy™ welcomes Dr. Dinender Singla, associate professor at the University of Central Florida’s Burnett School of Biomedical Sciences to discuss his recently published textbook, Stem Cell Biology: Basic Concepts to Frontiers, Students Edition and his work in stem cell research.

Biological cells found in all multicellular organisms, stem cells can divide (through mitosis) and differentiate into diverse specialized cell types and can self-renew to produce more stem cells. In mammals, there are two broad types of stem cells: embryonic stem cells and adult stem cells. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. In a developing embryo, stem cells can differentiate into all the specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues.

Since stem cells have the ability to differentiate into any type of cell, they offer something in the development of medical treatments for a wide range of conditions. Treatments that have been proposed include treatment for physical trauma, degenerative conditions, cardiac repair and genetic diseases (in combination with gene therapy). Yet further treatments using stem cells could potentially be developed thanks to their ability to repair extensive tissue damage.

Stem cells are a hot-button issue in medical science. The status of human embryonic stem cell research is a controversial issue as, with the present state of technology, the creation of a human embryonic stem cell line requires the destruction of a human embryo. Stem cell debates have motivated and reinvigorated the pro-life movement, whose members are concerned with the rights and status of the embryo as an early-aged human life. They can believe that embryonic stem cell research instrumentalizes and violates the sanctity of life and some also view it as tantamount to murder. The fundamental assertion of those who oppose embryonic stem cell research is the belief that human life is inviolable, combined with the belief that human life begins when a sperm cell fertilizes an egg cell to form a single cell.

“My goal was to create a textbook in simple language that undergraduates and graduates can understand,” said Dr. Singla, who is working with stem cells to determine if they can help a diseased heart heal itself. His research program has been supported by National Institutes of Health (NIH) grants. All of the book’s illustrations and photographs are in color, to help hold students’ attention. Dr. Singla used his own notes and also asked colleagues to contribute to the book, which describes a range of subjects from embryonic stem cells to adult stem cells – which turn only into cells from their tissue of origin – to regenerative medicine.   “The potential for stem cell biology is wide open,” said Dr. Singla, who received the 2012 University Award for Excellence in Research. “Students will need to have knowledge of this.”

Hour 2, Dr. Hildy™ and Shoshanna will discuss current applications of stem cell therapy – and use in cosmetics and every-day items.

Join Dr. Hildy™ and her guests, Dr. Singla and Shoshanna this week as they discuss stem cell research and education on One Cell One Light Radio!

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ALL Images above:  Stem Cell Biology: Basic Concepts to Frontiers – Students Edition (Vol 1): Dinender K Singla, Paolo DiNardo, 2012

Stem Cell Biology: Basic Concepts to Frontiers – Students Edition (Volume 1): Dinender K Singla,Paolo DiNardo: 9781466291072: Amazon.com
http://www.amazon.com/Biology-Concepts-Frontiers-Students-Edition/dp/1466291079#_

UCF College Of Medicine : Dr. Singla Authors Stem Cell Textbook
http://med.ucf.edu/news/2012/08/dr-singla-authors-stem-cell-textbook/

Sources of Ordinary Tissue For Nuclear Reprogramming fro ES Cells – chart
http://www.1cellonelight.com/pdf/SourcesofOrdinaryTissueforNucelarReprogrammingfromESCells.pdf

UCF Burnett School of Biomedical Sciences : Dr. Dinender Singla - Bio
 http://med.ucf.edu/biomed/directory/profile/dr-dinender-singla/

Singla DK[auth] – PubMed – NCBI – Twenty-Six Published Papers
http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=PubMed&term=%20Singla%20DK%5Bauth%5D

Which Cancer Treatment Works Best? Ask Your Personalized ‘Mini-Me’ Mice
http://www.care2.com/causes/which-cancer-treatment-works-best-ask-your-personalized-mice.html

Stem Cell Debate Hampers Science – Central Florida Future – University of Central Florida
http://www.centralfloridafuture.com/stem-cell-debate-hampers-science-1.1690729

Embryonic Stem Cells In Cardiac Repair And Regeneration
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788053/

Nobel Prize In Medicine – Gurdon and Yamanaka For Stem Cells
http://www.1cellonelight.com/pdf/Medicine-Nobel-Prize-in-Gurdon-and-Yamanaka-for-Stem-Cells.pdf

Stem Cell Therapy For Cardiac Disease: Pediatric Research http://www.nature.com/pr/journal/v71/n4-2/full/pr201161a.html

Embryonic Stem Cells [Stem Cell Information]
http://stemcells.nih.gov/NR/exeres/CF58BBAC-E8A3-407F-B83E-6A8C4CE40908.htm

Why Brain Tumors Are So Hard To Destroy:

The most common and aggressive brain tumor grows by turning normal brain cells into stem cells, which can continuously replicate and regrow a tumor with only a handful of cells left behind, new research finds.
http://www.foxnews.com/health/2012/10/19/why-brain-tumors-are-so-hard-to-destroy/